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Gare de Lyon-Part-Dieu to Brussels trains

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Trip Overview

The average train between Gare de Lyon-Part-Dieu and Brussels takes 3h 51m and the fastest train takes 3h 43m. The train service runs several times per day from Gare de Lyon-Part-Dieu to Brussels. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

3h 51m
Duration
750 km
Distance
€180
Average price
Every 4 hours
Frequency

Gare de Lyon-Part-Dieu to Brussels train times

Trains run every 4 hours between Gare de Lyon-Part-Dieu and Brussels. The earliest departure is at 5:50 AM in the morning, and the last departure from Gare de Lyon-Part-Dieu is at 7:00 PM which arrives into Brussels at 10:43 PM. All services run direct with no transfers required, and take on average 3h 51m. The schedules shown below are for the next available departures.

Departing Wednesday, November 11, 2026

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    train train 3h 53m • Direct
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    train train 3h 44m • Direct
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    train train 4h 26m • Direct
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    train train 3h 43m • Direct
  • Show more

Departing Thursday, November 12, 2026

  •  → 

    train train 3h 53m • Direct
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    train train 3h 44m • Direct
  •  → 

    train train 4h 26m • Direct
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    train train 3h 43m • Direct
  • Show more

Departing Friday, November 13, 2026

  •  → 

    train train 3h 53m • Direct
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    train train 3h 44m • Direct
  •  → 

    train train 4h 26m • Direct
  •  → 

    train train 3h 43m • Direct
  • Show more

Departing Saturday, November 14, 2026

  •  → 

    train train 3h 53m • Direct
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    train train 3h 44m • Direct
  •  → 

    train train 4h 26m • Direct
  •  → 

    train train 3h 43m • Direct
  • Show more

Departing Sunday, November 15, 2026

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    train train 3h 44m • Direct
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    train train 4h 26m • Direct
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    train train 3h 43m • Direct
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    train train 3h 43m • Direct
  • Show more

Departing Monday, November 16, 2026

  •  → 

    train train 3h 53m • Direct
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    train train 3h 44m • Direct
  •  → 

    train train 4h 26m • Direct
  •  → 

    train train 3h 43m • Direct
  • Show more

Departing Tuesday, November 17, 2026

  •  → 

    train train 3h 53m • Direct
  •  → 

    train train 3h 44m • Direct
  •  → 

    train train 4h 26m • Direct
  •  → 

    train train 3h 43m • Direct
  • Show more

Frequently asked questions

Want to know about travelling from Gare de Lyon-Part-Dieu to Brussels? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Gare de Lyon-Part-Dieu to Brussels.ExpandLaunch map view
  • Distance: 750 km
  • Duration: 3h 51m

What companies run services between Gare de Lyon-Part-Dieu, France and Brussels, Belgium?

TGV inOui operates a train from Lyon Part Dieu to Brussel-Zuid / Bruxelles-Midi hourly. Tickets cost €150–230 and the journey takes 3h 50m. Belgian Railways (NMBS/SNCB) also services this route 6 times a week.

Operators