Gare de Lyon-Part-Dieu to Brussels Central Station Trains

Gare de Lyon-Part-Dieu to Brussels Central Station trains

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Trip Overview

The average train between Gare de Lyon-Part-Dieu and Brussels Central Station takes 4h 17m and the fastest train takes 3h 52m. The train service runs several times per day from Gare de Lyon-Part-Dieu to Brussels Central Station. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

4h 17m
Duration: 752 km
Distance: €182
Average price: Every 4 hours
Frequency

Train (TGV)

best

Take the train from Lyon Part Dieu to Brussel-Zuid / Bruxelles-Miditrain Tgv

4h 1m

€155–243

Gare de Lyon-Part-Dieu to Brussels Central Station train times

Trains run every 4 hours between Gare de Lyon-Part-Dieu and Brussels Central Station. The earliest departure is at 5:42 AM in the morning, and the last departure from Gare de Lyon-Part-Dieu is at 7:00 PM which arrives into Brussels Central Station at 11:03 PM. All services require a transfer, and take on average 4h 17m. The schedules shown below are for the next available departures.

Departing Sunday, August 23, 2026

8:27 AM → 12:44 PM
4h 17m • 1 change
11:00 AM → 4:13 PM
5h 13m • 1 change
2:00 PM → 6:44 PM
4h 44m • 1 change
4:59 PM → 8:51 PM
3h 52m • 1 change
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Departing Monday, August 24, 2026

5:42 AM → 9:54 AM
4h 12m • 1 change
8:27 AM → 12:32 PM
4h 5m • 1 change
11:00 AM → 3:47 PM
4h 47m • 1 change
2:00 PM → 6:27 PM
4h 27m • 1 change
Show more

Departing Tuesday, August 25, 2026

5:42 AM → 9:54 AM
4h 12m • 1 change
8:27 AM → 12:32 PM
4h 5m • 1 change
11:00 AM → 3:47 PM
4h 47m • 1 change
2:00 PM → 6:27 PM
4h 27m • 1 change
Show more

Departing Wednesday, August 26, 2026

5:42 AM → 9:54 AM
4h 12m • 1 change
8:27 AM → 12:32 PM
4h 5m • 1 change
11:00 AM → 3:47 PM
4h 47m • 1 change
2:00 PM → 6:27 PM
4h 27m • 1 change
Show more

Departing Thursday, August 27, 2026

5:42 AM → 9:54 AM
4h 12m • 1 change
8:27 AM → 12:32 PM
4h 5m • 1 change
11:00 AM → 3:47 PM
4h 47m • 1 change
2:00 PM → 6:27 PM
4h 27m • 1 change
Show more

Departing Friday, August 28, 2026

5:42 AM → 9:54 AM
4h 12m • 1 change
8:27 AM → 12:32 PM
4h 5m • 1 change
11:00 AM → 3:47 PM
4h 47m • 1 change
2:00 PM → 6:27 PM
4h 27m • 1 change
Show more

Departing Saturday, August 29, 2026

5:42 AM → 9:52 AM
4h 10m • 1 change
8:27 AM → 12:31 PM
4h 4m • 1 change
11:00 AM → 3:44 PM
4h 44m • 1 change
2:00 PM → 6:27 PM
4h 27m • 1 change
Show more

Frequently asked questions

Want to know about travelling from Gare de Lyon-Part-Dieu to Brussels Central Station? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.