The average train between Gare du Nord and Lyon takes 2h 33m and the fastest train takes 2h 19m. There is a train service every few hours from Gare du Nord to Lyon. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run hourly between Gare du Nord and Lyon. The earliest departure is at 5:36 AM in the morning, and the last departure from Gare du Nord is at 10:36 PM which arrives into Lyon at 8:54 AM. All services require a transfer, and take on average 2h 33m. The schedules shown below are for the next available departures.

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2h 24m • 1 changeWant to know about travelling from Gare du Nord to Lyon? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Gare du Nord to Lyon. However, there are services departing from Paris Gare De Lyon station and arriving at Lyon Perrache station via Lyon Perrache station. The journey, including transfers, takes approximately 2h 33m.
Gare du Nord to Lyon train services, operated by TGV inOui, depart from Paris Gare De Lyon station.
Gare du Nord to Lyon train services, operated by TGV inOui, arrive at Lyon Perrache station.
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The distance between Gare du Nord and Lyon is 395.6 km. The road distance is 466 km.
TGV inOui operates a train from Paris Gare De Lyon to Lyon Perrache hourly. Tickets cost €85–130 and the journey takes 2h 10m. Two other operators also service this route.