The average train between Genoa and Santa Maria Novella takes 3h 46m and the fastest train takes 2h 43m. There is a train service every few hours from Genoa to Santa Maria Novella. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run hourly between Genoa and Santa Maria Novella. The earliest departure is at 5:14 AM in the morning, and the last departure from Genoa is at 8:57 PM which arrives into Santa Maria Novella at 5:28 AM. All services require a transfer at Pisa Centrale and take an average of 3h 46m. The schedules shown below are for the next available departures.

3h 20m • 1 change

3h 3m • 1 change

4h 4m • 1 change

3h 18m • 1 change

2h 43m • 1 change

3h 4m • 1 change

3h 21m • 1 change

4h 1m • 1 change

2h 43m • 1 change

3h 4m • 1 change

4h 8m • 1 change

3h 32m • 1 change

3h 24m • 1 change

3h 4m • 1 change

4h 8m • 1 change

3h 32m • 1 change
Want to know about travelling from Genoa to Santa Maria Novella? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Genoa to Santa Maria Novella. However, there are services departing from Genoa station and arriving at Santa Maria Novella station via Pisa Centrale. The journey, including transfers, takes approximately 3h 46m.
Genoa to Santa Maria Novella train services, operated by Trenitalia Intercity, depart from Genova Brignole station.
Genoa to Santa Maria Novella train services, operated by Trenitalia Intercity, arrive at Firenze S.M.N. station.
Book your Genoa to Santa Maria Novella train tickets online with Trenitalia Intercity, Trenitalia and Trenitalia Frecce.
The distance between Genoa and Santa Maria Novella is 197 km. The road distance is 237 km.
You can take a train from Genova Brignole to Santa Maria Novella via Pisa Centrale and Firenze S.M.N. in around 3h 26m.