The average train between Genoa and Sesto Calende takes 4h 24m and the fastest train takes 3h 12m. The train service runs several times per day from Genoa to Sesto Calende. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run every 4 hours between Genoa and Sesto Calende. The earliest departure is at 9:18 AM in the morning, and the last departure from Genoa is at 9:44 PM which arrives into Sesto Calende at 7:04 AM. All services require a transfer at Milano Centrale and take an average of 4h 24m. The schedules shown below are for the next available departures.


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4h 13m • 2 changesWant to know about travelling from Genoa to Sesto Calende? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Genoa to Sesto Calende. However, there are services departing from Genova P.Za Principe station and arriving at Sesto Calende station via Milano Centrale station. The journey, including transfers, takes approximately 4h 24m.
Genoa to Sesto Calende train services, operated by Trenitalia Intercity, depart from Genova P.Za Principe station.
Genoa to Sesto Calende train services, operated by Trenitalia, arrive at Sesto Calende station.
Book your Genoa to Sesto Calende train tickets online with Omio.
The distance between Genoa and Sesto Calende is 148.7 km. The road distance is 174 km.
You can take a train from Genova P.Za Principe to Sesto Calende via Milano Centrale and Rho-Fiera Milano in around 3h 51m.