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Greenville Station to Chicago trains

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Trip Overview

The train between Greenville Station and Chicago takes 33h 2m. The train runs, on average, 3 times per week from Greenville Station to Chicago. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

33h 2m
Duration
1,173 mi
Distance
$338
Average price
3 times a week
Frequency

Greenville Station to Chicago train times

Trains run 3 times a week between Greenville Station and Chicago. The earliest departure is at 2:23 AM at night, and the last departure from Greenville Station is at 2:23 AM which arrives into Chicago at 10:25 AM. All services require a transfer, and take on average 33h 2m. The schedules shown below are for the next available departures.

Departing Friday, October 9, 2026

  •  → 

    Arrives next day

    AmtrakAmtrak33h 2m • 1 change

Departing Sunday, October 11, 2026

  •  → 

    Arrives next day

    AmtrakAmtrak33h 2m • 1 change

Departing Wednesday, October 14, 2026

  •  → 

    Arrives next day

    AmtrakAmtrak33h 2m • 1 change

Frequently asked questions

Want to know about travelling from Greenville Station to Chicago? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Greenville Station to Chicago.ExpandLaunch map view
  • Distance: 1,172.6 mi
  • Duration: 33h 2m

What companies run services between Greenville Station, SC, USA and Chicago, IL, USA?

You can take a train from Greenville Amtrak Station to Chicago Union Station via Charlottesville in around 30h 24m.

Operators