The average train between Grenoble and Karlsruhe takes 9h 7m and the fastest train takes 6h 29m. The train service runs several times per day from Grenoble to Karlsruhe. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run 4 times a day between Grenoble and Karlsruhe. The earliest departure is at 6:21 AM in the morning, and the last departure from Grenoble is at 4:21 PM which arrives into Karlsruhe at 9:26 AM. All services require a transfer at Lyon Part Dieu and take an average of 9h 7m. The schedules shown below are for the next available departures.


6h 34m • 2 changes


6h 29m • 2 changes


8h 1m • 2 changes


7h 35m • 2 changes


7h 4m • 2 changes


6h 29m • 2 changes


8h 31m • 2 changes


7h 35m • 2 changes


7h 4m • 2 changes


6h 29m • 2 changes


7h 31m • 2 changes


7h 35m • 2 changes


6h 34m • 2 changes


6h 29m • 2 changes


8h 1m • 2 changes
Arrives next day


17h 5m • 2 changes
Want to know about travelling from Grenoble to Karlsruhe? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Grenoble to Karlsruhe. However, there are services departing from Grenoble station and arriving at Karlsruhe station via Lyon Part Dieu. The journey, including transfers, takes approximately 9h 7m.
Grenoble to Karlsruhe train services, operated by Société Nationale des Chemins de fer Français (SNCF), depart from Grenoble station.
Grenoble to Karlsruhe train services, operated by Société Nationale des Chemins de fer Français (SNCF), arrive at Karlsruhe Hbf station.
Book your Grenoble to Karlsruhe train tickets online with Société Nationale des Chemins de fer Français (SNCF), TGV inOui and Deutsche Bahn Intercity (DB IC).
The distance between Grenoble and Karlsruhe is 472 km. The road distance is 714 km.
You can take a train from Grenoble to Karlsruhe Hbf via Lyon Part Dieu and Strasbourg in around 7h 35m.