The average train between Grenoble and Santander takes 20h 59m and the fastest train takes 14h 58m. The train service runs several times per day from Grenoble to Santander. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run twice daily between Grenoble and Santander. The earliest departure is at 8:30 AM in the morning, and the last departure from Grenoble is at 3:29 PM which arrives into Santander at 6:04 PM. All services require a transfer at Valence Tgv Rhone-Alpes Sud and take an average of 20h 59m. The schedules shown below are for the next available departures.




14h 58m • 4 changes
Arrives next day




22h 19m • 4 changes
Arrives next day




26h 35m • 4 changes




14h 58m • 4 changes
Arrives next day




22h 36m • 4 changes
Arrives next day




26h 35m • 4 changes




14h 58m • 4 changes
Arrives next day




22h 36m • 4 changes
Arrives next day




26h 35m • 4 changes
Want to know about travelling from Grenoble to Santander? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Grenoble to Santander. However, there are services departing from Grenoble station and arriving at Santander station via Valence Tgv Rhone-Alpes Sud. The journey, including transfers, takes approximately 20h 59m.
Grenoble to Santander train services, operated by Zou! Lignes Express Régionales, depart from Grenoble station.
Grenoble to Santander train services, operated by Zou! Lignes Express Régionales, arrive at Santander station.
Book your Grenoble to Santander train tickets online with Zou! Lignes Express Régionales, TGV inOui and 5 other operators.
The distance between Grenoble and Santander is 780.4 km. The road distance is 1,717 km.
You can take a train from Grenoble to Santander via Valence Tgv Rhone-Alpes Sud, Barcelona-Sants, Madrid-Puerta de Atocha-Almudena Grandes, Madrid-Atocha Cercanías, and Madrid Chamartín in around 16h 1m.