The average train between Grosseto and Brindisi takes 8h 22m and the fastest train takes 7h 45m. The train service runs several times per day from Grosseto to Brindisi. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run 4 times a day between Grosseto and Brindisi. The earliest departure is at 5:18 AM in the morning, and the last departure from Grosseto is at 9:25 PM which arrives into Brindisi at 1:57 PM. All services require a transfer, and take on average 8h 22m. The schedules shown below are for the next available departures.

8h 6m • 1 change

7h 45m • 1 change

7h 56m • 1 change

7h 51m • 1 change

8h 39m • 1 change

8h 6m • 1 change

7h 45m • 1 change

7h 56m • 1 change

8h 39m • 1 change

8h 6m • 1 change

7h 45m • 1 change

7h 56m • 1 change

8h 6m • 1 change

7h 45m • 1 change

7h 56m • 1 change

7h 51m • 1 change

8h 36m • 1 change

8h 6m • 1 change

7h 45m • 1 change

7h 56m • 1 change
Want to know about travelling from Grosseto to Brindisi? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Grosseto to Brindisi. However, there are services departing from Grosseto station and arriving at Brindisi station via Roma Termini. The journey, including transfers, takes approximately 8h 22m.
Grosseto to Brindisi train services, operated by Trenitalia, depart from Grosseto station.
Grosseto to Brindisi train services, operated by Trenitalia, arrive at Brindisi station.
Book your Grosseto to Brindisi train tickets online with Trenitalia, Trenitalia Frecce and Trenitalia Intercity.
The distance between Grosseto and Brindisi is 614.1 km. The road distance is 773 km.
You can take a train from Grosseto to Brindisi via Roma Termini in around 8h 4m.