The average train between Guadalajara and Santander takes 9h 29m and the fastest train takes 6h 2m. The train service runs several times per day from Guadalajara to Santander. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run 3 times a day between Guadalajara and Santander. The earliest departure is at 10:51 AM in the morning, and the last departure from Guadalajara is at 10:10 PM which arrives into Santander at 12:05 PM. All services require a transfer, and take on average 9h 29m. The schedules shown below are for the next available departures.

6h 2m • 1 change

9h 31m • 1 change
Arrives next day

13h 56m • 1 change

7h 13m • 1 change

9h 31m • 1 change
Arrives next day

13h 56m • 1 change

7h 13m • 1 change

9h 31m • 1 change
Arrives next day

13h 56m • 1 change
Want to know about travelling from Guadalajara to Santander? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Guadalajara to Santander. However, there are services departing from Guadalajara station and arriving at Santander station via Madrid Chamartín. The journey, including transfers, takes approximately 9h 29m.
Guadalajara to Santander train services, operated by Renfe Viajeros, depart from Guadalajara station.
Guadalajara to Santander train services, operated by Renfe Viajeros, arrive at Santander station.
Book your Guadalajara to Santander train tickets online with Renfe Viajeros.
The distance between Guadalajara and Santander is 319.8 km. The road distance is 505 km.
You can take a train from Guadalajara to Santander via Madrid Chamartín in around 6h 36m.