The average train between Guidonia and Florence takes 2h 50m and the fastest train takes 2h 5m. There is a train service every few hours from Guidonia to Florence. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run hourly between Guidonia and Florence. The earliest departure is at 5:26 AM in the morning, and the last departure from Guidonia is at 10:45 PM which arrives into Florence at 7:17 AM. All services require a transfer, and take on average 2h 50m. The schedules shown below are for the next available departures.

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2h 16m • 1 changeWant to know about travelling from Guidonia to Florence? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Guidonia to Florence. However, there are services departing from Guidonia Montecelio station and arriving at Firenze Santa Maria Novella station via Roma Tiburtina station. The journey, including transfers, takes approximately 2h 50m.
Guidonia to Florence train services, operated by Trenitalia, depart from Guidonia Montecelio station.
Guidonia to Florence train services, operated by ItaloTreno, arrive at Firenze Santa Maria Novella station.
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The distance between Guidonia and Florence is 232.1 km. The road distance is 269 km.
You can take a train from Guidonia Montecelio to Firenze Santa Maria Novella via Roma Tiburtina in around 2h 29m.