The average train between Hamburg and Karlsruhe takes 6h 13m and the fastest train takes 5h 22m. There is a train service every few hours from Hamburg to Karlsruhe. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run hourly between Hamburg and Karlsruhe. The earliest departure is at 4:27 AM at night, and the last departure from Hamburg is at 8:29 PM which arrives into Karlsruhe at 9:19 AM. All services require a transfer, and take on average 6h 13m. The schedules shown below are for the next available departures.

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5h 22m • 1 changeWant to know about travelling from Hamburg to Karlsruhe? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Hamburg to Karlsruhe. However, there are services departing from Hamburg Hbf station and arriving at Karlsruhe Hauptbahnhof station via Kassel Bahnhof Wilhelmshöhe station. The journey, including transfers, takes approximately 6h 13m.
Hamburg to Karlsruhe train services, operated by Deutsche Bahn Intercity (DB IC), depart from Hamburg Hbf station.
Hamburg to Karlsruhe train services, operated by Deutsche Bahn Intercity (DB IC), arrive at Karlsruhe Hauptbahnhof station.
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The distance between Hamburg and Karlsruhe is 516.9 km. The road distance is 610 km.
You can take a train from Hamburg Hbf to Karlsruhe Hauptbahnhof via Kassel Bahnhof Wilhelmshöhe in around 5h 41m.