The average train between Hamburg and Mannheim takes 4h 58m and the fastest train takes 4h 54m. There is an hourly train service from Hamburg to Mannheim. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run hourly between Hamburg and Mannheim. The earliest departure is at 4:27 AM at night, and the last departure from Hamburg is at 6:29 PM which arrives into Mannheim at 11:29 PM. All services require a transfer, and take on average 4h 58m. The schedules shown below are for the next available departures.

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Want to know about travelling from Hamburg to Mannheim? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Hamburg to Mannheim. However, there are services departing from Hamburg station and arriving at Mannheim station via Kassel Bahnhof Wilhelmshöhe. The journey, including transfers, takes approximately 4h 58m.
Hamburg to Mannheim train services, operated by Deutsche Bahn Intercity (DB IC), depart from Hamburg Hbf station.
Hamburg to Mannheim train services, operated by Deutsche Bahn Intercity (DB IC), arrive at Mannheim, Hauptbahnhof station.
Book your Hamburg to Mannheim train tickets online with Deutsche Bahn Intercity (DB IC).
The distance between Hamburg and Mannheim is 463.8 km. The road distance is 590 km.
You can take a train from Hamburg Hbf to Mannheim, Hauptbahnhof via Kassel Bahnhof Wilhelmshöhe in around 5h 5m.