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Harpers Ferry to St. Louis trains

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Trip Overview

The train between Harpers Ferry and St. Louis takes 22h 43m. The train runs, on average, 6 times per week from Harpers Ferry to St. Louis. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

22h 43m
Duration
994 mi
Distance
$641
Average price
6 times a week
Frequency

Harpers Ferry to St. Louis train times

Trains run 6 times a week between Harpers Ferry and St. Louis. The service departs Harpers Ferry at 5:08 PM in the evening, which arrives into St. Louis at 14:51:00. All services require a transfer, and take on average 22h 43m. The schedules shown below are for the next available departures.

Departing Sunday, November 8, 2026

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    Arrives next day

    AmtrakAmtrak22h 43m • 1 change

Departing Monday, November 9, 2026

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    Arrives next day

    AmtrakAmtrak22h 43m • 1 change

Departing Tuesday, November 10, 2026

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    Arrives next day

    AmtrakAmtrak22h 43m • 1 change

Departing Wednesday, November 11, 2026

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    Arrives next day

    AmtrakAmtrak22h 43m • 1 change

Departing Thursday, November 12, 2026

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    Arrives next day

    AmtrakAmtrak22h 43m • 1 change

Departing Friday, November 13, 2026

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    Arrives next day

    AmtrakAmtrak22h 43m • 1 change

Frequently asked questions

Want to know about travelling from Harpers Ferry to St. Louis? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Harpers Ferry to St. Louis.ExpandLaunch map view
  • Distance: 993.5 mi
  • Duration: 22h 43m

What companies run services between Harpers Ferry, WV, USA and St. Louis, MO, USA?

You can take a train from Harpers Ferry Amtrak to St. Louis via Chicago Union Station in around 22h 23m.

Operators