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Harrisburg, Pa to Buffalo trains

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Trip Overview

The average train between Harrisburg, Pa and Buffalo takes 14h 47m and the fastest train takes 11h 37m. The train service runs several times per day from Harrisburg, Pa to Buffalo. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

14h 47m
Duration
630 mi
Distance
$405
Average price
3 times a day
Frequency

Harrisburg, Pa to Buffalo train times

Trains run 3 times a day between Harrisburg, Pa and Buffalo. The earliest departure is at 6:40 AM in the morning, and the last departure from Harrisburg, Pa is at 9:15 PM which arrives into Buffalo at 3:32 PM. All services require a transfer, and take on average 14h 47m. The schedules shown below are for the next available departures.

Departing Monday, November 2, 2026

  •  → 

    AmtrakAmtrak12h 15m • 1 change
  •  → 

    AmtrakAmtrak11h 37m • 1 change
  •  → 

    Arrives next day

    AmtrakAmtrak19h 32m • 1 change

Departing Tuesday, November 3, 2026

  •  → 

    AmtrakAmtrak12h 15m • 1 change
  •  → 

    AmtrakAmtrak11h 37m • 1 change
  •  → 

    Arrives next day

    AmtrakAmtrak19h 32m • 1 change

Departing Wednesday, November 4, 2026

  •  → 

    AmtrakAmtrak12h 15m • 1 change
  •  → 

    AmtrakAmtrak11h 37m • 1 change
  •  → 

    Arrives next day

    AmtrakAmtrak19h 32m • 1 change

Departing Thursday, November 5, 2026

  •  → 

    AmtrakAmtrak12h 15m • 1 change
  •  → 

    AmtrakAmtrak11h 37m • 1 change
  •  → 

    Arrives next day

    AmtrakAmtrak19h 32m • 1 change

Departing Friday, November 6, 2026

  •  → 

    AmtrakAmtrak12h 15m • 1 change
  •  → 

    AmtrakAmtrak11h 37m • 1 change
  •  → 

    Arrives next day

    AmtrakAmtrak18h 17m • 1 change

Departing Saturday, November 7, 2026

  •  → 

    AmtrakAmtrak12h 12m • 1 change
  •  → 

    Arrives next day

    AmtrakAmtrak20h 27m • 1 change

Departing Sunday, November 8, 2026

  •  → 

    AmtrakAmtrak12h 12m • 1 change

Frequently asked questions

Want to know about travelling from Harrisburg, Pa to Buffalo? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Harrisburg, Pa to Buffalo.ExpandLaunch map view
  • Distance: 630.2 mi
  • Duration: 14h 47m

What companies run services between Harrisburg, Pa, PA, USA and Buffalo, NY, USA?

You can take a train from Harrisburg to Buffalo via Ny Moynihan Train Hall At Penn Station in around 13h 4m.

Operators