The average train between Heidelberg and Brindisi takes 20h 58m and the fastest train takes 16h 25m. The train service runs several times per day from Heidelberg to Brindisi. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run 4 times a day between Heidelberg and Brindisi. The earliest departure is at 2:02 AM at night, and the last departure from Heidelberg is at 10:14 PM which arrives into Brindisi at 8:27 PM. All services require a transfer at Mannheim, Hauptbahnhof and take an average of 20h 58m. The schedules shown below are for the next available departures.





16h 30m • 5 changes
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25h 15m • 5 changes
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20h 10m • 5 changes





18h • 5 changes





16h 25m • 5 changes
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25h 15m • 5 changes
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20h 10m • 5 changes





18h • 5 changes





16h 25m • 5 changes
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25h 15m • 5 changes
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24h 11m • 5 changes





18h 25m • 5 changes





16h 30m • 5 changes
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25h 15m • 5 changes
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24h 11m • 5 changes





18h 25m • 5 changes





16h 30m • 5 changes
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25h 15m • 5 changes
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24h 11m • 5 changes
Want to know about travelling from Heidelberg to Brindisi? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Heidelberg to Brindisi. However, there are services departing from Heidelberg station and arriving at Brindisi station via Basel SBB. The journey, including transfers, takes approximately 20h 58m.
Heidelberg to Brindisi train services, operated by Deutsche Bahn Regio (DB Regional), depart from Mannheim, Hauptbahnhof station.
Heidelberg to Brindisi train services, operated by Deutsche Bahn Regio (DB Regional), arrive at Brindisi station.
Book your Heidelberg to Brindisi train tickets online with Deutsche Bahn Regio (DB Regional), Deutsche Bahn Intercity (DB IC) and 4 other operators.
The distance between Heidelberg and Brindisi is 1,214.7 km. The road distance is 1,568 km.
You can take a train from Heidelberg, Hauptbahnhof to Brindisi via Mannheim, Hauptbahnhof, Basel SBB, Lugano, Milano Centrale, and Reggio Emilia Av in around 17h 56m.