The average train between Herisau and Karlsruhe takes 5h 12m and the fastest train takes 4h 44m. There is a train service every few hours from Herisau to Karlsruhe. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run every 2 hours between Herisau and Karlsruhe. The earliest departure is at 6:05 AM in the morning, and the last departure from Herisau is at 9:05 PM which arrives into Karlsruhe at 8:39 AM. All services require a transfer, and take on average 5h 12m. The schedules shown below are for the next available departures.

4h 44m • 1 change

4h 44m • 1 change

4h 44m • 1 change

4h 44m • 1 change

4h 44m • 1 change

4h 44m • 1 change

4h 44m • 1 change

4h 44m • 1 change

4h 44m • 1 change

4h 44m • 1 change

4h 44m • 1 change

4h 44m • 1 change

4h 44m • 1 change

4h 44m • 1 change

4h 44m • 1 change

4h 44m • 1 change
Want to know about travelling from Herisau to Karlsruhe? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Herisau to Karlsruhe. However, there are services departing from Herisau station and arriving at Karlsruhe station via Konstanz. The journey, including transfers, takes approximately 5h 12m.
Herisau to Karlsruhe train services, operated by Thurbo, depart from Herisau station.
Herisau to Karlsruhe train services, operated by Thurbo, arrive at Karlsruhe Hauptbahnhof station.
The distance between Herisau and Karlsruhe is 191.8 km. The road distance is 290 km.
You can take a train from Herisau to Karlsruhe Hauptbahnhof via Konstanz Bahnhof in around 4h 55m.