The average train between Hesse and Hamburg takes 3h 59m and the fastest train takes 3h 42m. There is a train service every few hours from Hesse to Hamburg. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run hourly between Hesse and Hamburg. The earliest departure is at 4:29 AM at night, and the last departure from Hesse is at 11:11 PM which arrives into Hamburg at 6:50 AM. All services require a transfer, and take on average 3h 59m. The schedules shown below are for the next available departures.

3h 53m • 1 change

3h 53m • 1 change

3h 55m • 1 change

3h 53m • 1 change

4h 1m • 1 change

3h 53m • 1 change

3h 53m • 1 change

3h 55m • 1 change

4h 44m • 1 change

3h 53m • 1 change

3h 53m • 1 change

3h 55m • 1 change
Want to know about travelling from Hesse to Hamburg? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Hesse to Hamburg. However, there are services departing from Hesse station and arriving at Hamburg station via Hamburg Hbf. The journey, including transfers, takes approximately 3h 59m.
Hesse to Hamburg train services, operated by Deutsche Bahn Regio (DB Regional), depart from Frankfurt station.
Hesse to Hamburg train services, operated by Deutsche Bahn Regio (DB Regional), arrive at Hamburg Hbf station.
Book your Hesse to Hamburg train tickets online with Deutsche Bahn Regio (DB Regional) and Deutsche Bahn Intercity (DB IC).
The distance between Hesse and Hamburg is 333.8 km. The road distance is 514 km.
Deutsche Bahn Intercity (DB IC) operates a train from Frankfurt to Hamburg Hbf hourly. Tickets cost €95–390 and the journey takes 3h 43m.