The average train between High Wycombe and Southampton takes 2h 50m and the fastest train takes 2h 23m. There is a train service every few hours from High Wycombe to Southampton. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run hourly between High Wycombe and Southampton. The earliest departure is at 12:30 AM at night, and the last departure from High Wycombe is at 9:12 PM which arrives into Southampton at 11:45 PM. All services require a transfer, and take on average 2h 50m. The schedules shown below are for the next available departures.

2h 30m • 1 change

2h 30m • 1 change

2h 30m • 1 change

2h 31m • 1 change

8h 11m • 1 change

2h 23m • 1 change

2h 37m • 1 change

2h 32m • 1 change

8h 11m • 1 change

2h 23m • 1 change

2h 37m • 1 change

2h 32m • 1 change

8h 11m • 1 change

2h 23m • 1 change

2h 37m • 1 change

2h 32m • 1 change
Want to know about travelling from High Wycombe to Southampton? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from High Wycombe to Southampton. However, there are services departing from High Wycombe station and arriving at Southampton station via Oxford. The journey, including transfers, takes approximately 2h 50m.
High Wycombe to Southampton train services, operated by Chiltern Railways, depart from High Wycombe station.
High Wycombe to Southampton train services, operated by Chiltern Railways, arrive at Southampton Central station.
Book your High Wycombe to Southampton train tickets online with Chiltern Railways and Cross Country.
The distance between High Wycombe and Southampton is 92.6 km. The road distance is 181 km.
You can take a train from High Wycombe to Southampton Central via Oxford in around 3h 1m.