The average train between Holyhead and High Wycombe takes 4h 43m and the fastest train takes 4h 35m. The train service runs several times per day from Holyhead to High Wycombe. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run 5 times a day between Holyhead and High Wycombe. The earliest departure is at 4:44 AM at night, and the last departure from Holyhead is at 5:53 PM which arrives into High Wycombe at 10:50 PM. All services require a transfer at London Euston and take an average of 4h 43m. The schedules shown below are for the next available departures.


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4h 35m • 2 changesWant to know about travelling from Holyhead to High Wycombe? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Holyhead to High Wycombe. However, there are services departing from Holyhead station and arriving at High Wycombe station via London Euston station. The journey, including transfers, takes approximately 4h 43m.
Holyhead to High Wycombe train services, operated by Avanti West Coast, depart from Holyhead station.
Holyhead to High Wycombe train services, operated by Chiltern Railways, arrive at High Wycombe station.
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The distance between Holyhead and High Wycombe is 322.7 km. The road distance is 378 km.
You can take a train from Holyhead to High Wycombe via London Euston, King's Cross St. Pancras station, Baker Street station, and London Marylebone in around 4h 43m.