The average train between Holyhead and Southgate takes 4h 17m and the fastest train takes 4h 12m. The train service runs several times per day from Holyhead to Southgate. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run 5 times a day between Holyhead and Southgate. The earliest departure is at 4:44 AM at night, and the last departure from Holyhead is at 5:53 PM which arrives into Southgate at 10:29 PM. All services require a transfer at London Euston and take an average of 4h 17m. The schedules shown below are for the next available departures.

4h 19m • 1 change

4h 17m • 1 change

4h 12m • 1 change

4h 18m • 1 change

4h 19m • 1 change

4h 17m • 1 change

4h 12m • 1 change

4h 18m • 1 change

4h 19m • 1 change

4h 17m • 1 change

4h 12m • 1 change

4h 18m • 1 change

4h 19m • 1 change

4h 17m • 1 change

4h 12m • 1 change

4h 18m • 1 change

4h 18m • 1 change

4h 15m • 1 change

4h 16m • 1 change

4h 15m • 1 change

4h 25m • 1 change

4h 16m • 1 change

4h 17m • 1 change

4h 16m • 1 change

4h 19m • 1 change

4h 17m • 1 change

4h 12m • 1 change

4h 18m • 1 change
Want to know about travelling from Holyhead to Southgate? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Holyhead to Southgate. However, there are services departing from Holyhead station and arriving at Southgate station via London Euston. The journey, including transfers, takes approximately 4h 17m.
Holyhead to Southgate train services, operated by Avanti West Coast, depart from Holyhead station.
Holyhead to Southgate train services, operated by Avanti West Coast, arrive at London Euston station.
The distance between Holyhead and Southgate is 358.1 km. The road distance is 436 km.
Avanti West Coast operates a train from Holyhead to London Euston 5 times a day. Tickets cost £90–160 and the journey takes 3h 48m.