The average train between Holyhead and Uxbridge takes 4h 46m and the fastest train takes 4h 42m. The train service runs several times per day from Holyhead to Uxbridge. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run 5 times a day between Holyhead and Uxbridge. The earliest departure is at 4:44 AM at night, and the last departure from Holyhead is at 5:53 PM which arrives into Uxbridge at 10:47 PM. All services require a transfer at London Euston and take an average of 4h 46m. The schedules shown below are for the next available departures.

4h 45m • 1 change

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4h 42m • 1 change

4h 54m • 1 change

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4h 42m • 1 change

4h 54m • 1 change

4h 45m • 1 change

4h 46m • 1 change

4h 42m • 1 change

4h 54m • 1 change

4h 45m • 1 change

4h 46m • 1 change

4h 42m • 1 change

4h 54m • 1 change

4h 46m • 1 change

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4h 46m • 1 change

4h 47m • 1 change

4h 57m • 1 change

4h 47m • 1 change

4h 48m • 1 change

4h 47m • 1 change
Want to know about travelling from Holyhead to Uxbridge? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Holyhead to Uxbridge. However, there are services departing from Holyhead station and arriving at Uxbridge station via London Euston. The journey, including transfers, takes approximately 4h 46m.
Holyhead to Uxbridge train services, operated by Avanti West Coast, depart from Holyhead station.
Holyhead to Uxbridge train services, operated by Avanti West Coast, arrive at London Euston station.
The distance between Holyhead and Uxbridge is 342.8 km. The road distance is 451 km.
Avanti West Coast operates a train from Holyhead to London Euston 5 times a day. Tickets cost £95–160 and the journey takes 3h 48m.