Rome2Rio

Indianapolis to Florence trains

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Trip Overview

The train between Indianapolis and Florence takes 26h 55m. The train runs, on average, 3 times per week from Indianapolis to Florence. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

26h 55m
Duration
1,109 mi
Distance
$720
Average price
3 times a week
Frequency

Indianapolis to Florence train times

Trains run 3 times a week between Indianapolis and Florence. The service departs Indianapolis at 12:15 AM at night, which arrives into Florence at 03:10:00. All services require a transfer, and take on average 26h 55m. The schedules shown below are for the next available departures.

Departing Wednesday, November 11, 2026

  •  → 

    Arrives next day

    AmtrakAmtrak26h 55m • 1 change

Departing Friday, November 13, 2026

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    Arrives next day

    AmtrakAmtrak26h 55m • 1 change

Departing Sunday, November 15, 2026

  •  → 

    Arrives next day

    AmtrakAmtrak26h 55m • 1 change

Frequently asked questions

Want to know about travelling from Indianapolis to Florence? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Indianapolis to Florence.ExpandLaunch map view
  • Distance: 1,109.1 mi
  • Duration: 26h 55m

What companies run services between Indianapolis, IN, USA and Florence, SC, USA?

You can take a train from Indianapolis to Florence Station via Alexandria in around 26h 41m.

Operators