The average train between Interlaken and Karlsruhe takes 4h 12m and the fastest train takes 3h 52m. There is a train service every few hours from Interlaken to Karlsruhe. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run hourly between Interlaken and Karlsruhe. The earliest departure is at 5:01 AM in the morning, and the last departure from Interlaken is at 7:04 PM which arrives into Karlsruhe at 11:40 PM. All services require a transfer, and take on average 4h 12m. The schedules shown below are for the next available departures.

3h 56m • 1 change

3h 52m • 1 change

3h 59m • 1 change

3h 59m • 1 change

3h 56m • 1 change

3h 52m • 1 change

3h 59m • 1 change

3h 59m • 1 change

3h 56m • 1 change

3h 52m • 1 change

3h 59m • 1 change

3h 59m • 1 change

3h 56m • 1 change

3h 52m • 1 change

3h 59m • 1 change

3h 59m • 1 change
Want to know about travelling from Interlaken to Karlsruhe? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Interlaken to Karlsruhe. However, there are services departing from Interlaken station and arriving at Karlsruhe station via Basel SBB. The journey, including transfers, takes approximately 4h 12m.
Interlaken to Karlsruhe train services, operated by SBB GmbH, depart from Interlaken West station.
Interlaken to Karlsruhe train services, operated by SBB GmbH, arrive at Karlsruhe Hauptbahnhof station.
Book your Interlaken to Karlsruhe train tickets online with SBB GmbH, Deutsche Bahn Intercity (DB IC) and Swiss Federal Railways (SBB CFF FFS).
The distance between Interlaken and Karlsruhe is 261.6 km. The road distance is 351 km.
You can take a train from Interlaken West to Karlsruhe Hauptbahnhof via Basel SBB in around 4h 4m.