The average train between Interlaken and Lake Iseo takes 13h 20m and the fastest train takes 8h 2m. The train service runs several times per day from Interlaken to Lake Iseo. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run 4 times a day between Interlaken and Lake Iseo. The earliest departure is at 5:34 AM in the morning, and the last departure from Interlaken is at 8:33 PM which arrives into Lake Iseo at 11:36 AM. All services require a transfer at Spiez and take an average of 13h 20m. The schedules shown below are for the next available departures.





8h 2m • 5 changes




8h 3m • 5 changes




9h 4m • 5 changes




9h 4m • 5 changesWant to know about travelling from Interlaken to Lake Iseo? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Interlaken to Lake Iseo. However, there are services departing from Interlaken station and arriving at Lake Iseo station via Domodossola. The journey, including transfers, takes approximately 13h 20m.
Interlaken to Lake Iseo train services, operated by BLS AG, depart from Spiez station.
Interlaken to Lake Iseo train services, operated by BLS AG, arrive at Brescia station.
Book your Interlaken to Lake Iseo train tickets online with BLS AG, Trenitalia and 4 other operators.
The distance between Interlaken and Lake Iseo is 201.2 km. The road distance is 350 km.
You can take a train from Interlaken West to Sulzano via Spiez, Domodossola, Milano Rogoredo, Milano Centrale, and Brescia in around 8h 17m.