The average train between Interlaken and Sesto Calende takes 5h 57m and the fastest train takes 3h 52m. The train service runs several times per day from Interlaken to Sesto Calende. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run twice daily between Interlaken and Sesto Calende. The earliest departure is at 1:32 PM in the afternoon, and the last departure from Interlaken is at 8:33 PM which arrives into Sesto Calende at 8:25 AM. All services require a transfer at Spiez and take an average of 5h 57m. The schedules shown below are for the next available departures.


3h 52m • 2 changes

3h 52m • 2 changes

3h 52m • 2 changes

3h 52m • 2 changes

3h 52m • 2 changes

3h 52m • 2 changesArrives next day


11h 52m • 2 changesWant to know about travelling from Interlaken to Sesto Calende? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Interlaken to Sesto Calende. However, there are services departing from Interlaken station and arriving at Sesto Calende station via Domodossola. The journey, including transfers, takes approximately 5h 57m.
Interlaken to Sesto Calende train services, operated by Swiss Federal Railways (SBB CFF FFS), depart from Spiez station.
Interlaken to Sesto Calende train services, operated by Swiss Federal Railways (SBB CFF FFS), arrive at Sesto Calende station.
Book your Interlaken to Sesto Calende train tickets online with Swiss Federal Railways (SBB CFF FFS), BLS AG and Trenitalia.
The distance between Interlaken and Sesto Calende is 122.5 km. The road distance is 180 km.
You can take a train from Interlaken West to Sesto Calende via Spiez and Domodossola in around 4h 39m.