The average train between Irvine and Santa Fe Depot takes 2h 36m and the fastest train takes 2h 16m. The train service runs several times per day from Irvine to Santa Fe Depot. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run every 3 hours between Irvine and Santa Fe Depot. The earliest departure is at 6:41 AM in the morning, and the last departure from Irvine is at 6:41 PM which arrives into Santa Fe Depot at 9:07 PM. All services require a transfer, and take on average 2h 36m. The schedules shown below are for the next available departures.

2h 23m • 1 change

2h 26m • 1 change

2h 26m • 1 change

3h 26m • 1 change

2h 23m • 1 change

2h 26m • 1 change

2h 26m • 1 change

3h 26m • 1 change

2h 23m • 1 change

2h 26m • 1 change

2h 26m • 1 change

3h 26m • 1 change

2h 23m • 1 change

2h 26m • 1 change

2h 26m • 1 change

3h 26m • 1 change

2h 35m • 1 change

2h 37m • 1 change

2h 16m • 1 change

3h 6m • 1 change

2h 35m • 1 change

2h 37m • 1 change

2h 16m • 1 change

3h 6m • 1 change
Want to know about travelling from Irvine to Santa Fe Depot? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Irvine to Santa Fe Depot. However, there are services departing from Irvine station and arriving at Santa Fe Depot station via San Diego. The journey, including transfers, takes approximately 2h 36m.
Irvine to Santa Fe Depot train services, operated by Metrolink Trains, depart from Irvine station.
Irvine to Santa Fe Depot train services, operated by Metrolink Trains, arrive at San Diego station.
The distance between Irvine and Santa Fe Depot is 122.1 km. The road distance is 141 km.
Amtrak operates a train from Irvine to San Diego hourly. Tickets cost $27–55 and the journey takes 1h 55m.