The average train between Iseo and Florence takes 3h 16m and the fastest train takes 3h 8m. The train service runs several times per day from Iseo to Florence. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run 5 times a day between Iseo and Florence. The earliest departure is at 5:36 AM in the morning, and the last departure from Iseo is at 4:36 PM which arrives into Florence at 7:54 PM. All services require a transfer at Brescia and take an average of 3h 16m. The schedules shown below are for the next available departures.


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3h 18m • 2 changesWant to know about travelling from Iseo to Florence? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Iseo to Florence. However, there are services departing from Iseo station and arriving at Florence station via Brescia. The journey, including transfers, takes approximately 3h 16m.
Iseo to Florence train services, operated by Trenord, depart from Iseo station.
Iseo to Florence train services, operated by Trenord, arrive at Firenze Santa Maria Novella station.
Book your Iseo to Florence train tickets online with Trenord, ItaloTreno and Trenitalia Frecce.
The distance between Iseo and Florence is 229.4 km. The road distance is 296 km.
You can take a train from Iseo to Firenze Santa Maria Novella via Brescia and Verona Porta Nuova in around 3h 55m.