Iseo to Siena Trains

Trip Overview

The average train between Iseo and Siena takes 6h 31m and the fastest train takes 5h 7m. The train service runs several times per day from Iseo to Siena. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

6h 31m
Duration: 390 km
Distance: €60
Average price: Every 4 hours
Frequency

Train

best

Take the train from Brescia to Verona Porta Nuovatrain Fr
Take the train from Verona Porta Nuova to Firenze S.M.N.train Fr
Take the train from Firenze S.M.N. to Sienatrain Re

6h 17m

€47–85

Iseo to Siena train times

Trains run every 4 hours between Iseo and Siena. The earliest departure is at 5:36 AM in the morning, and the last departure from Iseo is at 8:36 PM which arrives into Siena at 10:40 AM. All services require a transfer at Brescia and take an average of 6h 31m. The schedules shown below are for the next available departures.

Departing Monday, November 2, 2026

5:31 PM → 11:16 PM
5h 45m • 3 changes
8:36 PM → 10:40 AM
Arrives next day
14h 4m • 3 changes

Departing Tuesday, November 3, 2026

5:36 AM → 11:40 AM
6h 4m • 3 changes
7:31 AM → 12:38 PM
5h 7m • 3 changes
7:48 AM → 1:40 PM
5h 52m • 3 changes
12:36 PM → 6:40 PM
6h 4m • 3 changes
Show more

Departing Wednesday, November 4, 2026

5:36 AM → 11:40 AM
6h 4m • 3 changes
7:31 AM → 12:38 PM
5h 7m • 3 changes
7:48 AM → 1:40 PM
5h 52m • 3 changes
12:36 PM → 6:40 PM
6h 4m • 3 changes
Show more

Departing Thursday, November 5, 2026

5:36 AM → 11:40 AM
6h 4m • 3 changes
7:31 AM → 12:38 PM
5h 7m • 3 changes
7:48 AM → 1:40 PM
5h 52m • 3 changes
12:36 PM → 6:40 PM
6h 4m • 3 changes
Show more

Departing Friday, November 6, 2026

5:36 AM → 11:40 AM
6h 4m • 3 changes
7:31 AM → 12:38 PM
5h 7m • 3 changes
7:48 AM → 1:40 PM
5h 52m • 3 changes
12:36 PM → 6:40 PM
6h 4m • 3 changes
Show more

Departing Saturday, November 7, 2026

5:36 AM → 11:40 AM
6h 4m • 3 changes
7:31 AM → 12:38 PM
5h 7m • 3 changes
7:48 AM → 1:40 PM
5h 52m • 3 changes
12:36 PM → 6:40 PM
6h 4m • 3 changes
Show more

Departing Sunday, November 8, 2026

7:31 AM → 12:38 PM
5h 7m • 3 changes
7:36 AM → 1:40 PM
6h 4m • 3 changes
12:36 PM → 6:40 PM
6h 4m • 3 changes
2:36 PM → 8:40 PM
6h 4m • 3 changes
Show more

Frequently asked questions

Want to know about travelling from Iseo to Siena? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.