The average train between Iserlohn and Wuppertal takes 1h and the fastest train takes 53 min. There is a train service every few hours from Iserlohn to Wuppertal. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run hourly between Iserlohn and Wuppertal. The earliest departure is at 5:20 AM in the morning, and the last departure from Iserlohn is at 11:48 PM which arrives into Wuppertal at 12:55 AM. All services require a transfer, and take on average 1h. The schedules shown below are for the next available departures.

53 min • 1 change

1h 7m • 1 change

53 min • 1 change

53 min • 1 change

53 min • 1 change

1h 7m • 1 change

53 min • 1 change

53 min • 1 change

53 min • 1 change

1h 7m • 1 change

53 min • 1 change

53 min • 1 change
Want to know about travelling from Iserlohn to Wuppertal? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Iserlohn to Wuppertal. However, there are services departing from Iserlohn station and arriving at Wuppertal station via Hagen Hbf. The journey, including transfers, takes approximately 1h.
Iserlohn to Wuppertal train services, operated by VIAS Rail GmbH, depart from Iserlohn station.
Iserlohn to Wuppertal train services, operated by VIAS Rail GmbH, arrive at Wuppertal Hbf station.
Book your Iserlohn to Wuppertal train tickets online with VIAS Rail GmbH, Deutsche Bahn Intercity (DB IC) and 2 other operators.
The distance between Iserlohn and Wuppertal is 40.8 km. The road distance is 53 km.
You can take a train from Iserlohn to Wuppertal Hbf via Hagen Hbf in around 43 min.