The average train between Isernia and Anzio takes 4h 56m and the fastest train takes 3h 16m. The train service runs several times per day from Isernia to Anzio. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run 5 times a day between Isernia and Anzio. The earliest departure is at 6:35 AM in the morning, and the last departure from Isernia is at 8:35 PM which arrives into Anzio at 7:46 AM. All services require a transfer, and take on average 4h 56m. The schedules shown below are for the next available departures.

4h 9m • 1 change

4h 6m • 1 change

3h 41m • 1 change

3h 44m • 1 change

4h 9m • 1 change

4h 6m • 1 change

3h 41m • 1 change

3h 44m • 1 change

4h 9m • 1 change

4h 6m • 1 change

3h 41m • 1 change

3h 44m • 1 change

4h 9m • 1 change

4h 6m • 1 change

3h 41m • 1 change

3h 44m • 1 change

4h 9m • 1 change

4h 6m • 1 change

3h 41m • 1 change

3h 44m • 1 change

3h 47m • 1 change

4h 4m • 1 change

3h 41m • 1 change

3h 42m • 1 change
Want to know about travelling from Isernia to Anzio? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Isernia to Anzio. However, there are services departing from Isernia station and arriving at Anzio station via Roma Termini. The journey, including transfers, takes approximately 4h 56m.
Isernia to Anzio train services, operated by Trenitalia, depart from Isernia station.
Isernia to Anzio train services, operated by Trenitalia, arrive at Anzio Colonia station.
Book your Isernia to Anzio train tickets online with Trenitalia.
The distance between Isernia and Anzio is 135.2 km. The road distance is 240 km.
You can take a train from Isernia to Anzio Colonia via Roma Termini in around 3h 48m.