The average train between Isernia and Bologna takes 6h 7m and the fastest train takes 4h 30m. The train service runs several times per day from Isernia to Bologna. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run 4 times a day between Isernia and Bologna. The earliest departure is at 6:35 AM in the morning, and the last departure from Isernia is at 8:35 PM which arrives into Bologna at 8:03 AM. All services require a transfer, and take on average 6h 7m. The schedules shown below are for the next available departures.

4h 33m • 1 change

4h 30m • 1 change

5h • 1 change
Arrives next day

11h 28m • 1 change

4h 33m • 1 change

4h 30m • 1 change

5h • 1 change
Arrives next day

11h 28m • 1 change

4h 33m • 1 change

4h 30m • 1 change

5h • 1 change
Arrives next day

11h 28m • 1 change

4h 33m • 1 change

4h 30m • 1 change

5h • 1 change
Arrives next day

11h 28m • 1 change
Want to know about travelling from Isernia to Bologna? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Isernia to Bologna. However, there are services departing from Isernia station and arriving at Bologna station via Roma Termini. The journey, including transfers, takes approximately 6h 7m.
Isernia to Bologna train services, operated by Trenitalia, depart from Isernia station.
Isernia to Bologna train services, operated by Trenitalia, arrive at Bologna centrale station.
Book your Isernia to Bologna train tickets online with Trenitalia and ItaloTreno.
The distance between Isernia and Bologna is 398.9 km. The road distance is 535 km.
You can take a train from Isernia to Bologna centrale via Roma Termini in around 4h 36m.