The average train between Isernia and Brussels takes 23h 44m and the fastest train takes 22h 17m. The train service runs several times per day from Isernia to Brussels. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run twice daily between Isernia and Brussels. The earliest departure is at 8:38 AM in the morning, and the last departure from Isernia is at 5:27 PM which arrives into Brussels at 3:44 PM. All services require a transfer at Roma Termini and take an average of 23h 44m. The schedules shown below are for the next available departures.
Want to know about travelling from Isernia to Brussels? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Isernia to Brussels. However, there are services departing from Isernia station and arriving at Brussel-Zuid / Bruxelles-Midi station via Roma Termini station, Milano Centrale station and Paris Gare De Lyon station. The journey, including transfers, takes approximately 23h 44m.
Isernia to Brussels train services, operated by Trenitalia, depart from Isernia station.
Isernia to Brussels train services, operated by Eurostar, arrive at Brussel-Zuid / Bruxelles-Midi station.
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The distance between Isernia and Brussels is 1277.2 km. The road distance is 1580 km.
You can take a train from Isernia to Brussel-Zuid / Bruxelles-Midi via Roma Termini, Milano Centrale, Paris Gare de Lyon, and Paris Nord in around 15h 25m.