The average train between Isernia and Florence takes 4h and the fastest train takes 3h 56m. There is at least one train per day from Isernia to Florence. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run once daily between Isernia and Florence. The earliest departure is at 6:35 AM in the morning, and the last departure from Isernia is at 1:28 PM which arrives into Florence at 5:31 PM. All services require a transfer, and take on average 4h. The schedules shown below are for the next available departures.
Want to know about travelling from Isernia to Florence? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Isernia to Florence. However, there are services departing from Isernia station and arriving at Florence station via Roma Tiburtina. The journey, including transfers, takes approximately 4h.
Isernia to Florence train services, operated by Trenitalia, depart from Isernia station.
Isernia to Florence train services, operated by Trenitalia, arrive at Firenze Santa Maria Novella station.
Book your Isernia to Florence train tickets online with Trenitalia and ItaloTreno.
The distance between Isernia and Florence is 344.3 km. The road distance is 441 km.
You can take a train from Isernia to Firenze Santa Maria Novella via Roma Tiburtina in around 4h 9m.