The average train between Isernia and Orvieto takes 6h 43m and the fastest train takes 4h 5m. The train service runs several times per day from Isernia to Orvieto. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run 5 times a day between Isernia and Orvieto. The earliest departure is at 6:35 AM in the morning, and the last departure from Isernia is at 8:35 PM which arrives into Orvieto at 7:23 AM. All services require a transfer, and take on average 6h 43m. The schedules shown below are for the next available departures.

4h 46m • 1 change

5h 10m • 1 change
Arrives next day

10h 48m • 1 change

5h 2m • 1 change

8h 8m • 1 change

4h 46m • 1 change

5h 10m • 1 change

5h 2m • 1 change

8h 8m • 1 change

4h 46m • 1 change

5h 10m • 1 change

5h 2m • 1 change

8h 8m • 1 change

4h 46m • 1 change

5h 10m • 1 change

5h 2m • 1 change

8h 8m • 1 change

4h 46m • 1 change

5h 10m • 1 change
Want to know about travelling from Isernia to Orvieto? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Isernia to Orvieto. However, there are services departing from Isernia station and arriving at Orvieto station via Roma Termini. The journey, including transfers, takes approximately 6h 43m.
Isernia to Orvieto train services, operated by Trenitalia, depart from Isernia station.
Isernia to Orvieto train services, operated by Trenitalia, arrive at Orvieto station.
Book your Isernia to Orvieto train tickets online with Trenitalia and Trenitalia Intercity.
The distance between Isernia and Orvieto is 214.9 km. The road distance is 296 km.
You can take a train from Isernia to Orvieto via Roma Termini in around 4h 20m.