The train between Isernia and Palermo takes 12h 17m. The train runs, on average, once a week from Isernia to Palermo. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run on demand between Isernia and Palermo. Service times information will be available soon. All services run direct with no transfers required, and take on average 12h 17m.
Want to know about travelling from Isernia to Palermo? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Isernia to Palermo. However, there are services departing from Isernia station and arriving at Palermo Centrale station via Napoli Afragola station. The journey, including transfers, takes approximately 12h 17m.
Isernia to Palermo train services, operated by Trenitalia, depart from Isernia station.
Isernia to Palermo train services, operated by Trenitalia Intercity, arrive at Palermo Centrale station.
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The distance between Isernia and Palermo is 392.7 km.
You can take a train from Isernia to Palermo Centrale via Napoli Afragola in around 12h 17m.