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Isleworth to Holyhead trains

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Trip Overview

The average train between Isleworth and Holyhead takes 5h 2m and the fastest train takes 4h 40m. The train service runs several times per day from Isleworth to Holyhead. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

5h 2m
Duration
277 mi
Distance
£118
Average price
5 times a day
Frequency

Train

best
  1. Take the train from London Euston to Holyheadtrain train London Euston - Holyhead
5h 33m
£97–151

Isleworth to Holyhead train times

Trains run 5 times a day between Isleworth and Holyhead. The earliest departure is at 7:02 AM in the morning, and the last departure from Isleworth is at 6:50 PM which arrives into Holyhead at 11:53 PM. All services require a transfer at Vauxhall and take an average of 5h 2m. The schedules shown below are for the next available departures.

Departing Sunday, October 11, 2026

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    South Western RailwayLondon Underground (Tube)Avanti West Coast4h 40m • 2 changes

Departing Monday, October 12, 2026

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    South Western RailwayLondon Underground (Tube)Avanti West Coast4h 49m • 2 changes

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    South Western RailwayLondon Underground (Tube)Avanti West Coast5h 4m • 2 changes

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    South Western RailwayLondon Underground (Tube)Avanti West Coast5h 4m • 2 changes

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    South Western RailwayLondon Underground (Tube)Avanti West Coast5h 5m • 2 changes
  • Show more

Departing Tuesday, October 13, 2026

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    South Western RailwayLondon Underground (Tube)Avanti West Coast4h 49m • 2 changes

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    South Western RailwayLondon Underground (Tube)Avanti West Coast5h 4m • 2 changes

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    South Western RailwayLondon Underground (Tube)Avanti West Coast5h 4m • 2 changes

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    South Western RailwayLondon Underground (Tube)Avanti West Coast5h 5m • 2 changes
  • Show more

Departing Wednesday, October 14, 2026

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    South Western RailwayLondon Underground (Tube)Avanti West Coast4h 49m • 2 changes

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    South Western RailwayLondon Underground (Tube)Avanti West Coast5h 4m • 2 changes

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    South Western RailwayLondon Underground (Tube)Avanti West Coast5h 4m • 2 changes

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    South Western RailwayLondon Underground (Tube)Avanti West Coast5h 5m • 2 changes
  • Show more

Departing Thursday, October 15, 2026

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    South Western RailwayLondon Underground (Tube)Avanti West Coast4h 49m • 2 changes

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    South Western RailwayLondon Underground (Tube)Avanti West Coast5h 4m • 2 changes

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    South Western RailwayLondon Underground (Tube)Avanti West Coast5h 4m • 2 changes

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    South Western RailwayLondon Underground (Tube)Avanti West Coast5h 5m • 2 changes
  • Show more

Departing Friday, October 16, 2026

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    South Western RailwayLondon Underground (Tube)Avanti West Coast4h 49m • 2 changes

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    South Western RailwayLondon Underground (Tube)Avanti West Coast5h 4m • 2 changes

  •  → 

    South Western RailwayLondon Underground (Tube)Avanti West Coast5h 4m • 2 changes

  •  → 

    South Western RailwayLondon Underground (Tube)Avanti West Coast5h 5m • 2 changes
  • Show more

Departing Saturday, October 17, 2026

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    South Western RailwayLondon Underground (Tube)Avanti West Coast5h 3m • 2 changes

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    South Western RailwayLondon Underground (Tube)Avanti West Coast5h 2m • 2 changes

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    South Western RailwayLondon Underground (Tube)Avanti West Coast5h 3m • 2 changes

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    South Western RailwayLondon Underground (Tube)Avanti West Coast5h 3m • 2 changes
  • Show more

Frequently asked questions

Want to know about travelling from Isleworth to Holyhead? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Isleworth to Holyhead.ExpandLaunch map view
  • Distance: 276.7 mi
  • Duration: 5h 2m

What companies run services between Isleworth, England and Holyhead, Wales?

Avanti West Coast operates a train from London Euston to Holyhead 5 times a day. Tickets cost £90–140 and the journey takes 3h 52m.

Operators