The average train between Issy-les-Moulineaux and Brussels takes 1h 55m and the fastest train takes 1h 50m. There is a train service every few hours from Issy-les-Moulineaux to Brussels. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run hourly between Issy-les-Moulineaux and Brussels. The earliest departure is at 5:40 AM in the morning, and the last departure from Issy-les-Moulineaux is at 9:18 PM which arrives into Brussels at 11:17 PM. All services require a transfer at Gare du Nord and take an average of 1h 55m. The schedules shown below are for the next available departures.

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1h 53m • 1 changeWant to know about travelling from Issy-les-Moulineaux to Brussels? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Issy-les-Moulineaux to Brussels. However, there are services departing from Mairie de Montrouge station and arriving at Brussel-Zuid / Bruxelles-Midi station via Gare du Nord station. The journey, including transfers, takes approximately 1h 55m.
Issy-les-Moulineaux to Brussels train services, operated by RATP Metro, depart from Mairie de Montrouge station.
Issy-les-Moulineaux to Brussels train services, operated by Eurostar, arrive at Brussel-Zuid / Bruxelles-Midi station.
The distance between Issy-les-Moulineaux and Brussels is 270.2 km. The road distance is 304 km.
There is no direct connection from Issy-les-Moulineaux to Brussels. However, you can take the line 4 subway to Gare du Nord, walk to Paris Nord, then take the train to Brussel-Zuid / Bruxelles-Midi.