The average train between Italy and Karlsruhe takes 11h 49m and the fastest train takes 10h 27m. The train service runs several times per day from Italy to Karlsruhe. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run 4 times a day between Italy and Karlsruhe. The earliest departure is at 6:30 AM in the morning, and the last departure from Italy is at 8:05 PM which arrives into Karlsruhe at 1:57 PM. All services require a transfer at Milano Centrale and take an average of 11h 49m. The schedules shown below are for the next available departures.


10h 27m • 2 changes

10h 27m • 2 changes

10h 51m • 2 changesArrives next day


11h 15m • 2 changes

10h 27m • 2 changes

10h 27m • 2 changes

10h 51m • 2 changesArrives next day


11h 15m • 2 changes

10h 27m • 2 changes

10h 27m • 2 changes

10h 51m • 2 changesArrives next day


11h 15m • 2 changesWant to know about travelling from Italy to Karlsruhe? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Italy to Karlsruhe. However, there are services departing from Italy station and arriving at Karlsruhe station via Milano Centrale. The journey, including transfers, takes approximately 11h 49m.
Italy to Karlsruhe train services, operated by ItaloTreno, depart from Roma Termini station.
Italy to Karlsruhe train services, operated by ItaloTreno, arrive at Karlsruhe Hauptbahnhof station.
Book your Italy to Karlsruhe train tickets online with ItaloTreno, Trenitalia EuroCity and Deutsche Bahn Intercity (DB IC).
The distance between Italy and Karlsruhe is 781.6 km. The road distance is 1,136 km.
You can take a train from Roma Termini to Karlsruhe Hauptbahnhof via Milano Centrale and Basel SBB in around 10h 37m.