Karlovy Vary to Brno Trains

Karlovy Vary to Brno trains

Travel from

Search accommodation with Expedia

Trip Overview

The average train between Karlovy Vary and Brno takes 6h 49m and the fastest train takes 6h 16m. The train service runs several times per day from Karlovy Vary to Brno. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

6h 49m
Duration: 484 km
Distance: Kč 1,650
Average price: Every 3 hours
Frequency

Train

best

Take the train from Karlovy Vary to Praha Hlavni Nadrazitrain 607 / ...
Take the train from Praha Hlavni Nadrazi to Brno Hlavni Nadrazitrain Rj / ...

6h 12m

Kč 1,050–3,409

Karlovy Vary to Brno train times

Trains run every 3 hours between Karlovy Vary and Brno. The earliest departure is at 4:57 AM at night, and the last departure from Karlovy Vary is at 6:57 PM which arrives into Brno at 2:49 AM. All services require a transfer, and take on average 6h 49m. The schedules shown below are for the next available departures.

Departing Saturday, August 15, 2026

6:57 PM → 8:13 AM
Arrives next day
13h 16m • 1 change

Departing Sunday, August 16, 2026

5:50 AM → 12:13 PM
6h 23m • 1 change
6:57 AM → 1:40 PM
6h 43m • 1 change
8:57 AM → 3:13 PM
6h 16m • 1 change
10:57 AM → 5:13 PM
6h 16m • 1 change
Show more

Departing Monday, August 17, 2026

4:57 AM → 11:13 AM
6h 16m • 1 change
5:50 AM → 12:13 PM
6h 23m • 1 change
6:57 AM → 1:40 PM
6h 43m • 1 change
8:57 AM → 3:13 PM
6h 16m • 1 change
Show more

Departing Tuesday, August 18, 2026

4:57 AM → 11:13 AM
6h 16m • 1 change
5:50 AM → 12:13 PM
6h 23m • 1 change
6:57 AM → 1:40 PM
6h 43m • 1 change
8:57 AM → 3:13 PM
6h 16m • 1 change
Show more

Departing Wednesday, August 19, 2026

4:57 AM → 11:13 AM
6h 16m • 1 change
5:50 AM → 12:13 PM
6h 23m • 1 change
6:57 AM → 1:40 PM
6h 43m • 1 change
8:57 AM → 3:13 PM
6h 16m • 1 change
Show more

Departing Thursday, August 20, 2026

4:57 AM → 11:13 AM
6h 16m • 1 change
5:50 AM → 12:13 PM
6h 23m • 1 change
6:57 AM → 1:40 PM
6h 43m • 1 change
8:57 AM → 3:13 PM
6h 16m • 1 change
Show more

Departing Friday, August 21, 2026

4:57 AM → 11:13 AM
6h 16m • 1 change
5:50 AM → 12:13 PM
6h 23m • 1 change
6:57 AM → 1:40 PM
6h 43m • 1 change
8:57 AM → 3:13 PM
6h 16m • 1 change
Show more

Frequently asked questions

Want to know about travelling from Karlovy Vary to Brno? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.