The average train between Karlovy Vary and Brussels takes 12h 47m and the fastest train takes 9h 4m. The train service runs several times per day from Karlovy Vary to Brussels. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run every 4 hours between Karlovy Vary and Brussels. The earliest departure is at 5:50 AM in the morning, and the last departure from Karlovy Vary is at 6:08 PM which arrives into Brussels at 11:26 AM. All services require a transfer at Cheb and take an average of 12h 47m. The schedules shown below are for the next available departures.



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11h 4m • 3 changesWant to know about travelling from Karlovy Vary to Brussels? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Karlovy Vary to Brussels. However, there are services departing from Karlovy Vary station and arriving at Brussels-Nord station via Cheb station, Nuernberg Hbf station and Frankfurt station. The journey, including transfers, takes approximately 12h 47m.
Karlovy Vary to Brussels train services, operated by České dráhy (ČD), depart from Karlovy Vary station.
Karlovy Vary to Brussels train services, operated by Deutsche Bahn Intercity (DB IC), arrive at Brussels-Nord station.
Book your Karlovy Vary to Brussels train tickets online with Omio.
The distance between Karlovy Vary and Brussels is 605.8 km. The road distance is 740 km.
You can take a train from Karlovy Vary to Brussels-Nord via Cheb, Nuernberg Hbf, Nürnberg Hbf, and Frankfurt in around 10h 23m.