The average train between Karlovy Vary and Mannheim takes 9h and the fastest train takes 7h 35m. The train service runs several times per day from Karlovy Vary to Mannheim. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run every 4 hours between Karlovy Vary and Mannheim. The earliest departure is at 5:50 AM in the morning, and the last departure from Karlovy Vary is at 6:08 PM which arrives into Mannheim at 9:29 AM. All services require a transfer at Cheb and take an average of 9h. The schedules shown below are for the next available departures.



7h 35m • 3 changes


8h 22m • 3 changes


7h 35m • 3 changes


7h 35m • 3 changes


7h 35m • 3 changes


8h 22m • 3 changes


7h 35m • 3 changes


7h 35m • 3 changes


7h 35m • 3 changes


8h 22m • 3 changes


7h 35m • 3 changes


7h 35m • 3 changes


7h 35m • 3 changes


8h 22m • 3 changes


7h 35m • 3 changes


7h 35m • 3 changes


7h 35m • 3 changes


8h 22m • 3 changes


7h 35m • 3 changes


7h 35m • 3 changes


8h 7m • 3 changes


8h 22m • 3 changes


7h 35m • 3 changes


7h 35m • 3 changes


8h 7m • 3 changes


8h 22m • 3 changes


7h 35m • 3 changes


7h 35m • 3 changesWant to know about travelling from Karlovy Vary to Mannheim? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Karlovy Vary to Mannheim. However, there are services departing from Karlovy Vary station and arriving at Mannheim, Hauptbahnhof station via Cheb station, Nuernberg Hbf station and Frankfurt station. The journey, including transfers, takes approximately 9h.
Karlovy Vary to Mannheim train services, operated by České dráhy (ČD), depart from Karlovy Vary station.
Karlovy Vary to Mannheim train services, operated by Deutsche Bahn Intercity (DB IC), arrive at Mannheim, Hauptbahnhof station.
Book your Karlovy Vary to Mannheim train tickets online with Omio.
The distance between Karlovy Vary and Mannheim is 326.3 km. The road distance is 412 km.
You can take a train from Karlovy Vary to Mannheim, Hauptbahnhof via Cheb, Nuernberg Hbf, Nürnberg Hbf, and Frankfurt in around 7h 10m.