The average train between Karlovy Vary and Mannheim takes 7h 1m and the fastest train takes 6h 35m. The train service runs several times per day from Karlovy Vary to Mannheim. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run every 4 hours between Karlovy Vary and Mannheim. The earliest departure is at 5:50 AM in the morning, and the last departure from Karlovy Vary is at 6:08 PM which arrives into Mannheim at 1:21 AM. All services require a transfer at Cheb and take an average of 7h 1m. The schedules shown below are for the next available departures.



7h 35m • 3 changes



6h 35m • 3 changes
Arrives next day



7h 47m • 3 changes



7h 7m • 3 changes



7h 22m • 3 changes



6h 35m • 3 changes



6h 35m • 3 changes



6h 35m • 3 changes



7h 22m • 3 changes



6h 35m • 3 changes



6h 35m • 3 changes



6h 35m • 3 changes



7h 22m • 3 changes



6h 35m • 3 changes



6h 35m • 3 changes



6h 35m • 3 changes



7h 22m • 3 changes



6h 35m • 3 changes



6h 35m • 3 changes



6h 35m • 3 changes



7h 22m • 3 changes



6h 35m • 3 changes



6h 35m • 3 changes



6h 35m • 3 changes



7h 22m • 3 changes



6h 35m • 3 changes



6h 35m • 3 changes
Want to know about travelling from Karlovy Vary to Mannheim? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Karlovy Vary to Mannheim. However, there are services departing from Karlovy Vary station and arriving at Mannheim station via Cheb. The journey, including transfers, takes approximately 7h 1m.
Karlovy Vary to Mannheim train services, operated by České dráhy (ČD), depart from Karlovy Vary station.
Karlovy Vary to Mannheim train services, operated by České dráhy (ČD), arrive at Mannheim, Hauptbahnhof station.
Book your Karlovy Vary to Mannheim train tickets online with České dráhy (ČD), Deutsche Bahn Intercity (DB IC) and Deutsche Bahn Regio (DB Regional).
The distance between Karlovy Vary and Mannheim is 326.3 km. The road distance is 503 km.
You can take a train from Karlovy Vary to Mannheim, Hauptbahnhof via Cheb, Nuernberg Hbf, Nürnberg Hbf, and Frankfurt in around 7h 11m.