The average train between Karlovy Vary and Plzeň Region takes 3h 23m and the fastest train takes 2h 46m. The train service runs several times per day from Karlovy Vary to Plzeň Region. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run every 4 hours between Karlovy Vary and Plzeň Region. The earliest departure is at 4:22 AM at night, and the last departure from Karlovy Vary is at 4:22 PM which arrives into Plzeň Region at 8:36 PM. All services require a transfer, and take on average 3h 23m. The schedules shown below are for the next available departures.

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Want to know about travelling from Karlovy Vary to Plzeň Region? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Karlovy Vary to Plzeň Region. However, there are services departing from Karlovy Vary station and arriving at Plzeň Region station via Plzen-Jizni Predmesti. The journey, including transfers, takes approximately 3h 23m.
Karlovy Vary to Plzeň Region train services, operated by České dráhy (ČD), depart from Karlovy Vary station.
Karlovy Vary to Plzeň Region train services, operated by České dráhy (ČD), arrive at Plzen-Jizni Predmesti station.
Book your Karlovy Vary to Plzeň Region train tickets online with České dráhy (ČD).
The distance between Karlovy Vary and Plzeň Region is 63.7 km. The road distance is 166 km.
České dráhy (ČD) operates a train from Karlovy Vary to Plzen-Jizni Predmesti hourly. Tickets cost Kč 450–700 and the journey takes 1h 57m.