Karlsruhe Hauptbahnhof to Brussels Trains

Karlsruhe Hauptbahnhof to Brussels trains

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Trip Overview

The average train between Karlsruhe Hauptbahnhof and Brussels takes 5h 16m and the fastest train takes 4h 36m. The train service runs several times per day from Karlsruhe Hauptbahnhof to Brussels. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

5h 16m
Duration: 519 km
Distance: €118
Average price: Every 4 hours
Frequency

Train via Cologne

best

Take the train from Karlsruhe Hauptbahnhof to Köln Hbftrain 43 / ...
Take the train from Köln Hbf to Bruxelles Miditrain 79

4h 47m

€84–241

Karlsruhe Hauptbahnhof to Brussels train times

Trains run every 4 hours between Karlsruhe Hauptbahnhof and Brussels. The earliest departure is at 1:24 AM at night, and the last departure from Karlsruhe Hauptbahnhof is at 8:59 PM which arrives into Brussels at 8:35 AM. All services require a transfer, and take on average 5h 16m. The schedules shown below are for the next available departures.

Departing Saturday, November 7, 2026

12:59 PM → 5:35 PM
4h 36m • 1 change
2:59 PM → 7:35 PM
4h 36m • 1 change
4:59 PM → 9:35 PM
4h 36m • 1 change
6:59 PM → 11:35 PM
4h 36m • 1 change

Departing Sunday, November 8, 2026

1:24 AM → 9:35 AM
8h 11m • 1 change
6:59 AM → 11:35 AM
4h 36m • 1 change
8:59 AM → 1:35 PM
4h 36m • 1 change
10:59 AM → 3:35 PM
4h 36m • 1 change
Show more

Departing Monday, November 9, 2026

1:24 AM → 8:35 AM
7h 11m • 1 change
6:59 AM → 11:35 AM
4h 36m • 1 change
8:59 AM → 1:35 PM
4h 36m • 1 change
10:59 AM → 3:35 PM
4h 36m • 1 change
Show more

Departing Tuesday, November 10, 2026

6:59 AM → 11:35 AM
4h 36m • 1 change
8:59 AM → 1:35 PM
4h 36m • 1 change
10:59 AM → 3:35 PM
4h 36m • 1 change
12:59 PM → 5:35 PM
4h 36m • 1 change
Show more

Departing Wednesday, November 11, 2026

6:59 AM → 11:35 AM
4h 36m • 1 change
8:59 AM → 1:35 PM
4h 36m • 1 change
10:59 AM → 3:35 PM
4h 36m • 1 change
12:59 PM → 5:35 PM
4h 36m • 1 change
Show more

Departing Thursday, November 12, 2026

6:59 AM → 11:35 AM
4h 36m • 1 change
8:59 AM → 1:35 PM
4h 36m • 1 change
10:59 AM → 3:35 PM
4h 36m • 1 change
12:59 PM → 5:35 PM
4h 36m • 1 change
Show more

Departing Friday, November 13, 2026

6:59 AM → 11:35 AM
4h 36m • 1 change
8:59 AM → 1:35 PM
4h 36m • 1 change
10:59 AM → 3:35 PM
4h 36m • 1 change
12:59 PM → 5:35 PM
4h 36m • 1 change
Show more

Frequently asked questions

Want to know about travelling from Karlsruhe Hauptbahnhof to Brussels? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.