Karlsruhe Hbf to Mainz, Hauptbahnhof train times
Trains run hourly between Karlsruhe Hbf and Mainz, Hauptbahnhof. The earliest departure is at 12:28 AM at night, and the last departure from Karlsruhe Hbf is at 11:18 PM which arrives into Mainz, Hauptbahnhof at 1:22 AM. All services require a transfer, and take on average 1h 54m. The schedules shown below are for the next available departures.
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1h 59m • 1 change
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1h 19m • 1 change
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1h 16m • 1 change
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1h 19m • 1 change
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Departing Thursday, August 20, 2026
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3h 19m • 1 change
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4h 14m • 1 change
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2h 43m • 1 change
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2h 10m • 1 change
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Departing Friday, August 21, 2026
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2h 22m • 1 change
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3h 25m • 1 change
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2h 25m • 1 change
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1h 44m • 1 change
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#/media/File:ICE_4_Berlin_Hauptbahnhof_(3).jpg "ICE 4 Berlin Hauptbahnhof")
