The average train between Karlsruhe Hbf and Prague takes 10h 30m and the fastest train takes 9h 15m. The train service runs several times per day from Karlsruhe Hbf to Prague. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run 5 times a day between Karlsruhe Hbf and Prague. The earliest departure is at 7:06 AM in the morning, and the last departure from Karlsruhe Hbf is at 7:06 PM which arrives into Prague at 10:21 AM. All services require a transfer at Nürnberg Hbf and take an average of 10h 30m. The schedules shown below are for the next available departures.


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9h 16m • 2 changesWant to know about travelling from Karlsruhe Hbf to Prague? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Karlsruhe Hbf to Prague. However, there are services departing from Karlsruhe Hbf station and arriving at Prague station via Nürnberg Hbf. The journey, including transfers, takes approximately 10h 30m.
Karlsruhe Hbf to Prague train services, operated by Deutsche Bahn Intercity (DB IC), depart from Karlsruhe Hauptbahnhof station.
Karlsruhe Hbf to Prague train services, operated by Deutsche Bahn Intercity (DB IC), arrive at Praha Hlavni Nadrazi station.
Book your Karlsruhe Hbf to Prague train tickets online with Deutsche Bahn Intercity (DB IC), Deutsche Bahn Regio (DB Regional) and Die Länderbahn.
The distance between Karlsruhe Hbf and Prague is 450.9 km. The road distance is 623 km.
You can take a train from Karlsruhe Hauptbahnhof to Praha Hlavni Nadrazi via Nürnberg Hbf, Nürnberg Hbf, and Schwandorf in around 9h 18m.