Karlsruhe Hbf to Prague Trains

Karlsruhe Hbf to Prague trains

Travel from

Search accommodation with Expedia

Trip Overview

The average train between Karlsruhe Hbf and Prague takes 10h 27m and the fastest train takes 9h 15m. There is at least one train per day from Karlsruhe Hbf to Prague. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

10h 27m
Duration: 623 km
Distance: Kč 3,458
Average price: Once daily
Frequency

Train

best

Take the train from Karlsruhe Hauptbahnhof to Nürnberg Hbftrain 61
Take the train from Nürnberg Hbf to Schwandorftrain
Take the train from Schwandorf to Praha Hlavni Nadrazitrain Re

9h 18m

Kč 2,862–6,426

Karlsruhe Hbf to Prague train times

Trains run once daily between Karlsruhe Hbf and Prague. The earliest departure is at 7:06 AM in the morning, and the last departure from Karlsruhe Hbf is at 7:06 PM which arrives into Prague at 10:21 AM. All services require a transfer at Nürnberg Hbf and take an average of 10h 27m. The schedules shown below are for the next available departures.

Departing Tuesday, October 20, 2026

7:06 PM → 10:21 AM
Arrives next day
15h 15m • 2 changes

Departing Wednesday, October 21, 2026

7:06 AM → 4:21 PM
9h 15m • 2 changes
9:06 AM → 6:21 PM
9h 15m • 2 changes
11:06 AM → 8:21 PM
9h 15m • 2 changes
1:06 PM → 10:22 PM
9h 16m • 2 changes
Show more

Departing Thursday, October 22, 2026

7:06 AM → 4:21 PM
9h 15m • 2 changes
9:06 AM → 6:21 PM
9h 15m • 2 changes
11:06 AM → 8:21 PM
9h 15m • 2 changes
1:06 PM → 10:22 PM
9h 16m • 2 changes

Frequently asked questions

Want to know about travelling from Karlsruhe Hbf to Prague? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.