Karlsruhe to Brussels Trains

Karlsruhe to Brussels trains

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Trip Overview

The average train between Karlsruhe and Brussels takes 4h 57m and the fastest train takes 4h 36m. The train service runs several times per day from Karlsruhe to Brussels. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

4h 57m
Duration: 519 km
Distance: €110
Average price: Every 4 hours
Frequency

Train via Cologne

best

Take the train from Karlsruhe Hauptbahnhof to Köln Hbftrain 43 / ...
Take the train from Köln Hbf to Bruxelles Miditrain 79

5h 8m

€90–401

Karlsruhe to Brussels train times

Trains run every 4 hours between Karlsruhe and Brussels. The earliest departure is at 1:24 AM at night, and the last departure from Karlsruhe is at 8:59 PM which arrives into Brussels at 8:38 AM. All services require a transfer, and take on average 4h 57m. The schedules shown below are for the next available departures.

Departing Tuesday, August 11, 2026

10:59 AM → 3:35 PM
4h 36m • 1 change
12:59 PM → 5:35 PM
4h 36m • 1 change
2:59 PM → 7:35 PM
4h 36m • 1 change
4:59 PM → 9:35 PM
4h 36m • 1 change
Show more

Departing Wednesday, August 12, 2026

1:24 AM → 9:35 AM
8h 11m • 1 change
6:59 AM → 11:35 AM
4h 36m • 1 change
8:59 AM → 1:35 PM
4h 36m • 1 change
10:59 AM → 3:35 PM
4h 36m • 1 change
Show more

Departing Thursday, August 13, 2026

1:24 AM → 9:35 AM
8h 11m • 1 change
6:59 AM → 11:35 AM
4h 36m • 1 change
8:59 AM → 1:35 PM
4h 36m • 1 change
10:59 AM → 3:35 PM
4h 36m • 1 change
Show more

Departing Friday, August 14, 2026

1:24 AM → 9:35 AM
8h 11m • 1 change
6:59 AM → 11:35 AM
4h 36m • 1 change
8:59 AM → 1:35 PM
4h 36m • 1 change
10:59 AM → 3:35 PM
4h 36m • 1 change
Show more

Departing Saturday, August 15, 2026

6:59 AM → 11:35 AM
4h 36m • 1 change
8:59 AM → 1:35 PM
4h 36m • 1 change
10:59 AM → 3:35 PM
4h 36m • 1 change
12:59 PM → 5:35 PM
4h 36m • 1 change
Show more

Departing Sunday, August 16, 2026

6:59 AM → 11:35 AM
4h 36m • 1 change
8:59 AM → 1:35 PM
4h 36m • 1 change
10:59 AM → 3:35 PM
4h 36m • 1 change
12:59 PM → 5:35 PM
4h 36m • 1 change
Show more

Departing Monday, August 17, 2026

6:59 AM → 11:35 AM
4h 36m • 1 change
8:59 AM → 1:35 PM
4h 36m • 1 change
10:59 AM → 3:35 PM
4h 36m • 1 change
12:59 PM → 5:35 PM
4h 36m • 1 change
Show more

Frequently asked questions

Want to know about travelling from Karlsruhe to Brussels? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.