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Karlsruhe to Domodossola trains

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Trip Overview

The average train between Karlsruhe and Domodossola takes 7h 16m and the fastest train takes 5h 11m. The train service runs several times per day from Karlsruhe to Domodossola. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

7h 16m
Duration
435 km
Distance
€144
Average price
Twice daily
Frequency

Karlsruhe to Domodossola train times

Trains run twice daily between Karlsruhe and Domodossola. The earliest departure is at 8:01 AM in the morning, and the last departure from Karlsruhe is at 11:26 PM which arrives into Domodossola at 9:12 AM. All services require a transfer, and take on average 7h 16m. The schedules shown below are for the next available departures.

Departing Monday, November 2, 2026

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    Arrives next day

    Deutsche Bahn Intercity (DB IC)Swiss Federal Railways (SBB CFF FFS)9h 46m • 1 change

Departing Tuesday, November 3, 2026

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    Deutsche Bahn Intercity (DB IC)Swiss Federal Railways (SBB CFF FFS)5h 11m • 1 change
  •  → 

    Arrives next day

    Deutsche Bahn Intercity (DB IC)Swiss Federal Railways (SBB CFF FFS)9h 46m • 1 change

Departing Wednesday, November 4, 2026

  •  → 

    Deutsche Bahn Intercity (DB IC)Swiss Federal Railways (SBB CFF FFS)5h 11m • 1 change
  •  → 

    Arrives next day

    Deutsche Bahn Intercity (DB IC)Swiss Federal Railways (SBB CFF FFS)9h 46m • 1 change

Departing Thursday, November 5, 2026

  •  → 

    Deutsche Bahn Intercity (DB IC)Swiss Federal Railways (SBB CFF FFS)5h 11m • 1 change
  •  → 

    Arrives next day

    Deutsche Bahn Intercity (DB IC)Swiss Federal Railways (SBB CFF FFS)9h 46m • 1 change

Departing Friday, November 6, 2026

  •  → 

    Deutsche Bahn Intercity (DB IC)Swiss Federal Railways (SBB CFF FFS)5h 11m • 1 change
  •  → 

    Arrives next day

    Deutsche Bahn Intercity (DB IC)Swiss Federal Railways (SBB CFF FFS)9h 46m • 1 change

Departing Saturday, November 7, 2026

  •  → 

    Deutsche Bahn Intercity (DB IC)Swiss Federal Railways (SBB CFF FFS)5h 11m • 1 change
  •  → 

    Deutsche Bahn Intercity (DB IC)Swiss Federal Railways (SBB CFF FFS)5h 11m • 1 change
  •  → 

    Arrives next day

    Deutsche Bahn Intercity (DB IC)Swiss Federal Railways (SBB CFF FFS)9h 46m • 1 change

Departing Sunday, November 8, 2026

  •  → 

    Deutsche Bahn Intercity (DB IC)Swiss Federal Railways (SBB CFF FFS)5h 11m • 1 change
  •  → 

    Deutsche Bahn Intercity (DB IC)Swiss Federal Railways (SBB CFF FFS)5h 11m • 1 change

Frequently asked questions

Want to know about travelling from Karlsruhe to Domodossola? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Karlsruhe to Domodossola.ExpandLaunch map view
  • Distance: 434.7 km
  • Duration: 7h 16m

What companies run services between Karlsruhe, Germany and Domodossola, Italy?

You can take a train from Karlsruhe Hauptbahnhof to Domodossola via Basel SBB in around 5h 30m.

Operators