The average train between Karlsruhe and Florence takes 12h 30m and the fastest train takes 8h 34m. The train service runs several times per day from Karlsruhe to Florence. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run 5 times a day between Karlsruhe and Florence. The earliest departure is at 9:01 AM in the morning, and the last departure from Karlsruhe is at 11:26 PM which arrives into Florence at 1:35 PM. All services require a transfer at Basel SBB and take an average of 12h 30m. The schedules shown below are for the next available departures.



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14h 34m • 3 changesWant to know about travelling from Karlsruhe to Florence? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Karlsruhe to Florence. However, there are services departing from Karlsruhe Hauptbahnhof station and arriving at Firenze Santa Maria Novella station via Basel SBB station, Lugano station and Milano Centrale station. The journey, including transfers, takes approximately 12h 30m.
Karlsruhe to Florence train services, operated by Deutsche Bahn Intercity (DB IC), depart from Karlsruhe Hauptbahnhof station.
Karlsruhe to Florence train services, operated by ItaloTreno, arrive at Firenze Santa Maria Novella station.
Book your Karlsruhe to Florence train tickets online with Omio.
The distance between Karlsruhe and Florence is 620.9 km. The road distance is 824 km.
You can take a train from Karlsruhe Hauptbahnhof to Firenze Santa Maria Novella via Basel SBB, Lugano, and Milano Centrale in around 10h 16m.