Karlsruhe to Italy trains

Travel from

Search accommodation with Expedia

Trip Overview

The average train between Karlsruhe and Italy takes 12h 42m and the fastest train takes 10h 4m. The train service runs several times per day from Karlsruhe to Italy. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

12h 42m
Duration: 1,103 km
Distance: €231
Average price: Every 4 hours
Frequency

Train

best

Take the train from Karlsruhe Hauptbahnhof to Basel SBBtrain 12 / ...
Take the train from Basel SBB to Luganotrain Ec
Take the train from Lugano to Milano Centraletrain
Take the train from Milano Centrale to Roma Terminitrain

11h 1m

€130–347

Karlsruhe to Italy train times

Trains run every 4 hours between Karlsruhe and Italy. The earliest departure is at 4:03 AM at night, and the last departure from Karlsruhe is at 11:26 PM which arrives into Italy at 1:24 PM. All services require a transfer at Basel SBB and take an average of 12h 42m. The schedules shown below are for the next available departures.

Departing Sunday, October 18, 2026

7:01 PM → 11:00 AM
Arrives next day
15h 59m • 3 changes

Departing Monday, October 19, 2026

4:04 AM → 4:19 PM
12h 15m • 3 changes
7:01 AM → 5:30 PM
10h 29m • 3 changes
9:01 AM → 7:19 PM
10h 18m • 3 changes
11:01 AM → 9:05 PM
10h 4m • 3 changes
Show more

Departing Tuesday, October 20, 2026

4:03 AM → 4:19 PM
12h 16m • 3 changes
7:01 AM → 5:30 PM
10h 29m • 3 changes
9:01 AM → 7:19 PM
10h 18m • 3 changes
11:01 AM → 9:05 PM
10h 4m • 3 changes
Show more

Departing Wednesday, October 21, 2026

4:03 AM → 4:19 PM
12h 16m • 3 changes
7:01 AM → 5:30 PM
10h 29m • 3 changes
9:01 AM → 7:19 PM
10h 18m • 3 changes
11:01 AM → 9:05 PM
10h 4m • 3 changes
Show more

Departing Thursday, October 22, 2026

4:03 AM → 4:19 PM
12h 16m • 3 changes
7:01 AM → 5:30 PM
10h 29m • 3 changes
9:01 AM → 7:19 PM
10h 18m • 3 changes
11:01 AM → 9:05 PM
10h 4m • 3 changes
Show more

Departing Friday, October 23, 2026

4:03 AM → 4:19 PM
12h 16m • 3 changes
7:01 AM → 5:30 PM
10h 29m • 3 changes
9:01 AM → 7:19 PM
10h 18m • 3 changes
11:01 AM → 9:05 PM
10h 4m • 3 changes
Show more

Departing Saturday, October 24, 2026

4:04 AM → 4:19 PM
12h 15m • 3 changes
7:01 AM → 5:30 PM
10h 29m • 3 changes
9:01 AM → 7:19 PM
10h 18m • 3 changes
11:01 AM → 9:05 PM
10h 4m • 3 changes
Show more

Frequently asked questions

Want to know about travelling from Karlsruhe to Italy? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.