The average train between Karlsruhe and Italy takes 13h 10m and the fastest train takes 10h 4m. The train service runs several times per day from Karlsruhe to Italy. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run every 4 hours between Karlsruhe and Italy. The earliest departure is at 7:01 AM in the morning, and the last departure from Karlsruhe is at 11:26 PM which arrives into Italy at 4:19 PM. All services require a transfer at Basel SBB and take an average of 13h 10m. The schedules shown below are for the next available departures.



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10h 23m • 3 changesWant to know about travelling from Karlsruhe to Italy? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Karlsruhe to Italy. However, there are services departing from Karlsruhe Hauptbahnhof station and arriving at Roma Termini station via Basel SBB station, Lugano station and Milano Centrale station. The journey, including transfers, takes approximately 13h 10m.
Karlsruhe to Italy train services, operated by Deutsche Bahn Intercity (DB IC), depart from Karlsruhe Hauptbahnhof station.
Karlsruhe to Italy train services, operated by ItaloTreno, arrive at Roma Termini station.
Book your Karlsruhe to Italy train tickets online with Omio.
The distance between Karlsruhe and Italy is 781.6 km. The road distance is 1098 km.
You can take a train from Karlsruhe Hauptbahnhof to Roma Termini via Basel SBB, Lugano, and Milano Centrale in around 11h 5m.